558.300—Ivermectin.

(a) Specifications. Type A medicated article containing 2.72 grams ivermectin per pound (g/lb).
(b) Sponsor. See No. 050604 in § 510.600(c) of this chapter.
(c) Related tolerances. See § 556.344 of this chapter.
(d) Special considerations. See § 500.25 of this chapter.
(e) Conditions of use in swine. It is used in feed as follows:
Ivermectin in g/ton of feed Combination in g/ton of feed Indications for use Limitations Sponsor
(1) 1.8 (to provide 0.1 milligram per kilogram (mg/kg) of body weight per day) Weaned, growing-finishing swine: For treatment and control of gastrointestinal roundworms (Ascaris suum, adults and fourth-stage larvae; Ascarops strongylina, adults; Hyostrongylus rubidus, adults and fourth-stage larvae; Oesophagostomum spp., adults and fourth-stage larvae); kidneyworms (Stephanurus dentatus, adults and fourth-stage larvae); lungworms (Metastrongylus spp., adults); threadworms (Strongyloides ransomi, adults and somatic larvae); lice (Haematopinus suis); and mange mites (Sarcoptes scabiei var. suis). Feed as the only feed for 7 consecutive days. Withdraw 5 days before slaughter. 050604
(2) 1.8 (to provide 0.1 mg/kg of body weight per day) Bacitracin methylene disalicylate, 10 to 30 Weaned, growing-finishing swine: As in paragraph (e)(1) of this section; and for increased rate of weight gain and improved feed efficiency. For use in swine feed only. Feed as the only feed for 7 consecutive days. Withdraw 5 days before slaughter. 050604
(3) 1.8 (to provide 0.1 mg/kg of body weight per day) Bacitracin methylene disalicylate, 250 Weaned, growing-finishing swine: As in paragraph (e)(1) of this section; and for control of swine dysentery associated with Treponema hyodysenteriae on premises with a history of swine dysentery, but where symptoms have not yet occurred, or following an approved treatment of disease condition. For use in swine feed only. Feed as the only feed for 7 consecutive days. Withdraw 5 days before slaughter. 050604
(4) 1.8 (to provide 0.1 mg/kg of body weight per day) Lincomycin, 20 Weaned, growing-finishing swine: For treatment and control of gastrointestinal roundworms (Ascaris suum, adults and fourth-stage larvae; Ascarops strongylina, adults; Hyostrongylus rubidus, adults and fourth-stage larvae; Oesophagostomum spp., adults and fourth-stage larvae); kidneyworms (Stephanurus dentatus, adults and fourth-stage larvae); lungworms (Metastrongylus spp., adults); lice (Haematopinus suis); and mange mites (Sarcoptes scabiei var. suis); and for increased rate of weight gain. Feed as the only feed for 7 consecutive days. Not to be fed to swine that weigh more than 250 lbs. Withdraw 5 days before slaughter. Also see paragraphs (c)(1) and (c)(2) in § 558.325 of this chapter. 050604
Code of Federal Regulations 439
(5) 1.8 (to provide 0.1 mg/kg of body weight per day) Lincomycin, 40 Weaned, growing-finishing swine: As in paragraph (e)(4) of this section; and for control of swine dysentery on premises with a history of swine dysentery, but where symptoms have not yet occurred. Feed as the only feed for 7 consecutive days. Not to be fed to swine that weigh more than 250 lbs. Also see paragraphs (c)(1) and (c)(2) in § 558.325 of this chapter. Withdraw 5 days before slaughter. A separate feed containing 40 g/ton lincomycin may be continued to complete the lincomycin treatment. 050604
(6) 1.8 (to provide 0.1 mg/kg of body weight per day) Lincomycin, 100 Weaned, growing-finishing swine: As in paragraph (e)(4) of this section; and for treatment of swine dysentery. Feed as the only feed for 7 consecutive days followed by a separate feed containing 100 g/ton lincomycin for an additional 14 days to complete the lincomycin treatment. Withdraw 6 days before slaughter. Not to be fed to swine that weigh more than 250 lbs. Also see paragraphs (c)(1) and (c)(2) in § 558.325 of this chapter. 050604
(7) 1.8 (to provide 0.1 mg/kg of body weight per day) Lincomycin, 200 Weaned, growing-finishing swine: As in paragraph (e)(4) of this section; and for reduction in severity of swine mycoplasmal pneumonia caused by Mycoplasma hyopneumoniae. Feed as the only feed for 7 consecutive days followed by a separate feed containing 200 g/ton lincomycin for an additional 14 days to complete the lincomycin treatment. Withdraw 6 days before slaughter. Not to be fed to swine that weigh more than 250 lbs. Also see paragraphs (c)(1) and (c)(2) in § 558.325 of this chapter. 050604
(8) 1.8 to 11.8 (to provide 0.1 mg/kg of body weight per day) Adult and breeding swine: For treatment and control of gastrointestinal roundworms (Ascaris suum, adults and fourth-stage larvae; Ascarops strongylina, adults; Hyostrongylus rubidus, adults and fourth-stage larvae; Oesophagostomum spp., adults and fourth-stage larvae); kidneyworms (Stephanurus dentatus, adults and fourth-stage larvae); lungworms (Metastrongylus spp., adults); threadworms (Strongyloides ransomi, adults and somatic larvae, and prevention of transmission of infective larvae to piglets, via the colostrum or milk, when fed during gestation); lice (Haematopinus suis); and mange mites (Sarcoptes scabiei var. suis). Feed as the only feed for 7 consecutive days. Withdraw 5 days before slaughter. 050604
Code of Federal Regulations 440
(9) 1.8 to 11.8 (to provide 0.1 mg/kg of body weight per day) Bacitracin methylene disalicylate, 250 Pregnant sows: As in paragraph (e)(8) of this section; and for control of clostridial enteritis caused by Clostridium perfringens in suckling piglets. Feed as the only feed for 7 consecutive days. Withdraw 5 days before slaughter. Feed bacitracin methylene disalicylate Type C medicated feed to sows from 14 days before through 21 days after farrowing on premises with a history of clostridial scours. 050604
(10) 18.2 to 120 (to provide 0.1 mg/kg of body weight per day) Adult and breeding swine: As in paragraph (e)(8) of this section. Top dress on daily ration for individual treatment for 7 consecutive days. Withdraw 5 days before slaughter. 050604

Code of Federal Regulations

[72 FR 37437, July 10, 2007]