CFR > Title 21 - Food and Drugs > CHAPTER I—FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES > SUBCHAPTER E—ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS (parts 500 to 590) > PART 556—TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD > SUBPART B—Specific Tolerances for Residues of New Animal Drugs (§556.34 to §556.770) > 556.344—Ivermectin.

556.344—Ivermectin.

(a) Acceptable daily intake (ADI). The ADI for total residues of ivermectin is 1 microgram per kilogram of body weight per day.
(b) Tolerances— (1) Liver. A tolerance is established for 22,23-dihydroavermectin B1 a (marker residue) in liver (target tissue) as follows:
(i) Cattle. 100 parts per billion.
(ii) Swine. 20 parts per billion.
(iii) Sheep. 30 parts per billion.
(iv) Reindeer. 15 parts per billion.
(v) American bison. 15 parts per billion.
(2) Muscle. Muscle residues are not indicative of the safety of other edible tissues. A tolerance is established for 22,23-dihydroavermectin B1 a (marker residue) in muscle as follows:
(i) Swine. 20 parts per billion.
(ii) Cattle. 10 parts per billion.

Code of Federal Regulations

[63 FR 54352, Oct. 9, 1998, as amended at 64 FR 26671, May 17, 1999]