522.2220—Sulfadimethoxine injection.
(a) Specifications.
Each milliliter of solution contains sodium sulfachlorpyridazine equivalent to 200 milligrams (mg) sulfachlorpyridazine.
(1) Amount.
Administer 30 to 45 mg per pound (/lb) of body weight in divided doses by twice daily injection for 1 to 5 days.
(2) Indications for use.
For the treatment of diarrhea caused or complicated by Escherichia coli (colibacillosis).
(3) Limitations.
Treated calves must not be slaughtered for food during treatment or for 5 days after the last treatment. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.
Code of Federal Regulations
(2) Sponsor.
(i)
See No. 000069 in § 510.600(c) of this chapter for conditions of use as in paragraphs (a)(3)(i) through (a)(3)(iii) of this section.
(a) For the treatment of respiratory, genitourinary tract, enteric, and soft tissue infections when caused by Streptococci, Staphylococci, Escherichia, Salmonella, Klebsiella, Proteus, or Shigella organisms sensitive to sulfadimethoxine, and in the treatment of canine bacterial enteritis associated with coccidiosis and canine Salmonellosis.
(b) It is administered by intravenous or subcutaneous injection at an initial dose of 55 milligrams per kilogram of body weight followed by 27.5 milligrams per kilogram of body weight every 24 hours.
(c) Federal law restricts this drug to use by or on the order of a licensed veterinarian.
(a) For the treatment of respiratory disease caused by Streptococcus equi (strangles).
(b) It is administered by intravenous injection at an initial dose of 55 milligrams per kilogram of body weight followed by 27.5 milligrams per kilogram of body weight every 24 hours until the patient is asymptomatic for 48 hours.
(c) Not for use in horses intended for food.
(d) Federal law restricts this drug to use by or on the order of a licensed veterinarian.
(a) For the treatment of shipping fever complex, bacterial pneumonia, calf diphtheria, and foot-rot.
(b) It is administered by intravenous injection at an initial dose of 25 milligrams per pound of body weight followed by 12.5 milligrams per pound of body weight every 24 hours until the animal is asymptomatic for 48 hours.
(c) Milk taken from animals during treatment and for 60 hours (5 milkings) after the latest treatment must not be used for food. Do not administer within 5 days of slaughter. A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.
(d) Tissue damage may result from perivascular infiltration.
(3) Conditions of use.
(i)
It is used or intended for use in the treatment of sulfadimethoxine-susceptible bacterial infections in dogs.
(ii)
It is administered by subcutaneous, intramuscular, or intravenous injection at an initial dose of 25 milligrams per pound of body weight followed by 12.5 milligrams per pound of body weight every 24 hours thereafter. Continue treatment until the animal is free from symptoms for 48 hours.