520.1921—Prochlorperazine, isopropamide, with neomycin sustained-release capsules.

(a) Specifications. Each capsule contains either:
(1) Capsule No. 1: 3.33 milligrams of prochlorperazine (as the dimaleate), 1.67 milligrams of isopropamide (as the iodide), and 25 milligrams of neomycin base (as the sulfate); or
(2) Capsule No. 3: 10 milligrams of prochlorperazine (as the dimaleate), 5 milligrams of isopropamide (as the iodide), and 75 milligrams of neomycin base (as the sulfate).
(b) Sponsor. See No. 000069 in § 510.600(c) of this chapter.
(c) Conditions of use— (1) Amount. Administer capsules orally twice daily to dogs as follows:
Animal weight (pounds) Number of capsules per dose
Capsule No. 1 Capsule No. 3
10 to 20 1
20 to 30 2
Over 30 3 1
Over 60 2
(2) Indications for use. For treatment of dogs in which infectious bacterial gastroenteritis is associated with emotional stress.
(3) Limitations. Do not continue medication longer than 5 days. Overdosage or prolonged administration may produce nephrotoxicity as manifested by albuminuria, presence of granular casts and depressed urinary output. If it is desirable to administer a vasoconstrictor, norepinephrine is the drug of choice. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Code of Federal Regulations

[49 FR 14103, Apr. 10, 1984, as amended at 56 FR 50653, Oct. 8, 1991; 60 FR 55659, Nov. 2, 1995]